Spontaneous remission of a diffuse brainstem lesion in a neonate

Pediatr Radiol. 2007 Apr;37(4):399-402. doi: 10.1007/s00247-007-0424-2. Epub 2007 Feb 23.


We describe here the spontaneous remission of a diffuse brainstem lesion found in an infant at the age of 7 weeks. Clinical and MRI characteristics strongly suggested a diffuse pontine glioma. Repeated MRI studies showed a continuous decrease in the size of the lesion, which was no longer visible by the age of 27 months. Spontaneous remission of diffuse pontine glioma is extremely rare; to our knowledge there are reports of only three similar cases.

Publication types

  • Case Reports

MeSH terms

  • Brain Stem Neoplasms / pathology*
  • Contrast Media
  • Follow-Up Studies
  • Gadolinium DTPA
  • Glioma / pathology*
  • Humans
  • Infant
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Neoplasm Regression, Spontaneous
  • Pons / pathology*


  • Contrast Media
  • Gadolinium DTPA