Paramutation: from maize to mice

Cell. 2007 Feb 23;128(4):641-5. doi: 10.1016/j.cell.2007.02.007.


Paramutation is the epigenetic transfer of information from one allele of a gene to another to establish a state of gene expression that is heritable for generations. RNA has recently emerged as a prominent mediator of this remarkable phenomenon in both maize and mice.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Alleles
  • Animals
  • Epigenesis, Genetic / genetics*
  • Gene Expression Regulation / genetics*
  • Heredity*
  • Humans
  • Mice
  • Mutation / genetics*
  • RNA / genetics*
  • Zea mays / genetics*


  • RNA