A clinicopathological study of eyelid malignancies from central India

Indian J Ophthalmol. 2007 Mar-Apr;55(2):109-12. doi: 10.4103/0301-4738.30703.


Background: Eyelid malignancies are completely treatable if detected early. The treatment depends on the invasiveness of the cancer which in turn depends on the type of malignancy.

Aim: The aim of the study was to characterize the distribution of the types of eyelid malignancies in central India.

Settings and design: The study was conducted in the Department of Plastic and Maxillofacial Surgery at a tertiary care hospital.

Materials and methods: We report a series of 27 cases of eyelid malignancies. In the same case series, we also include a case of malignant hemangiopericytoma which is an extremely rare form of eyelid malignancy worldwide.

Statistical analysis: Depending on the underlying statistical distribution, either analysis of variance (ANOVA) or the Kruskal-Wallis (K-W) test was used to assess the differential distribution of these variables across the types of eyelid malignancies observed in this study.

Results: We observed that sebaceous cell carcinoma (approximately 37%) was almost as prevalent as basal cell carcinoma (approximately 44%) in the study subjects and had an earlier age of occurrence and a more rapid clinical course.

Conclusions: Sebaceous cell carcinoma of the eyelid is almost as common as basal cell carcinoma in a large tertiary care centre in central India.

MeSH terms

  • Adenocarcinoma, Sebaceous / epidemiology
  • Adenocarcinoma, Sebaceous / pathology
  • Adenocarcinoma, Sebaceous / surgery
  • Biopsy, Fine-Needle
  • Carcinoma, Basal Cell / epidemiology
  • Carcinoma, Basal Cell / pathology
  • Carcinoma, Basal Cell / surgery
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery
  • Diagnosis, Differential
  • Eyelid Neoplasms* / epidemiology
  • Eyelid Neoplasms* / pathology
  • Eyelid Neoplasms* / surgery
  • Female
  • Hemangiopericytoma / epidemiology
  • Hemangiopericytoma / pathology
  • Hemangiopericytoma / surgery
  • Humans
  • India / epidemiology
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Ophthalmologic Surgical Procedures / methods
  • Prevalence
  • Prognosis
  • Retrospective Studies