Multiple photopigments entrain the Mammalian circadian oscillator

Neuron. 2007 Mar 1;53(5):619-21. doi: 10.1016/j.neuron.2007.02.017.


Circadian rhythms are entrained to the natural day:night cycle. Melanopsin expressed in retinal ganglion cells partially accounts for circadian photoentrainment. Dkhissi-Benyahya et al. demonstrate that medium wavelength opsin (MW-opsin) also plays an important role in the process. Furthermore, they develop a model explaining wavelength-dependent photoentrainment by melanopsin and MW-opsin.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Circadian Rhythm / physiology*
  • Humans
  • Light
  • Mammals
  • Retinal Ganglion Cells / physiology*
  • Rod Opsins / physiology*


  • Rod Opsins
  • melanopsin