The ketogenic diet: one decade later

Pediatrics. 2007 Mar;119(3):535-43. doi: 10.1542/peds.2006-2447.


The ketogenic diet, a high fat, adequate protein, low carbohydrate diet, has, during the past decade, had a resurgence of interest for the treatment of difficult-to-control seizures in children. This review traces its history, reviews its uses and side effects, and discusses possible alternatives and the diet's possible mechanisms of action. Finally, this review looks toward possible future uses of the ketogenic diet for conditions other than epilepsy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Child, Preschool
  • Clinical Protocols
  • Diet Therapy / standards
  • Diet Therapy / trends
  • Diet, Carbohydrate-Restricted*
  • Dietary Fats / administration & dosage*
  • Dietary Proteins / administration & dosage*
  • Epilepsy / diet therapy*
  • Forecasting
  • Humans
  • Patient Selection
  • Treatment Outcome
  • United States


  • Dietary Fats
  • Dietary Proteins