Pulmonary hypertension associated with left-sided heart disease

Clin Chest Med. 2007 Mar;28(1):233-41, x. doi: 10.1016/j.ccm.2006.12.001.


Pulmonary hypertension (PH) denotes a poor prognosis in patients with left-sided heart disease. No study has demonstrated long-term benefit from PH drugs such as prostanoids, endothelin antagonists, and phosphodiesterase-5 inhibitors. In some cases, cautious use of PH drugs may be indicated. However, theoretic and practical concerns limit any formal recommendations.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Comorbidity
  • Exercise Test
  • Heart Diseases / epidemiology*
  • Heart Diseases / surgery
  • Heart Transplantation
  • Humans
  • Hypertension, Pulmonary / classification
  • Hypertension, Pulmonary / diagnosis
  • Hypertension, Pulmonary / epidemiology*
  • Hypertension, Pulmonary / physiopathology
  • Prognosis
  • Ventricular Function, Left


  • Antihypertensive Agents