STRA6, a cell-surface receptor for retinol-binding protein: the plot thickens

Cell Metab. 2007 Mar;5(3):164-6. doi: 10.1016/j.cmet.2007.02.006.


How retinol (vitamin A) is taken up by cells has been an area of active research since the first report of a cell-surface receptor for retinol-binding protein (RBP) in the mid-1970s. Two recent reports, by Kawaguchi et al. (2007) and Pasutto et al. (2007), provide compelling data regarding the molecular identity and properties of a RBP receptor and open new research avenues for a better understanding of retinoid biology.

MeSH terms

  • Animals
  • Humans
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism*
  • Retinol-Binding Proteins / metabolism*
  • Vitamin A / metabolism


  • Membrane Proteins
  • Retinol-Binding Proteins
  • STRA6 protein, human
  • Stra6 protein, mouse
  • Vitamin A