Studies in the Chemical Constituents of Azadirachta indica Part II: Isolation and Structure of the New Triterpenoid Azadirachtol

S Siddiqui; B S Siddiqui; S Faizi

doi:10.1055/s-2007-969567

Studies in the Chemical Constituents of Azadirachta indica Part II: Isolation and Structure of the New Triterpenoid Azadirachtol

Planta Med. 1985 Dec;51(6):478-80. doi: 10.1055/s-2007-969567.

Authors

S Siddiqui¹, B S Siddiqui, S Faizi

Affiliation

¹ H. E. J. Research Institute of Chemistry, Universitiy of Karachi, Karachi-32/Pakistan.

PMID: 17345262
DOI: 10.1055/s-2007-969567

Abstract

A new triterpenoid named azadirachtol ( 1) has been isolated from the fruits of AZADIRACHTA INDICA Juss. (neem) of which the structure is reported on the basis of chemical and spectral data. Azadirachtol appears to be the first apo-tirucallol (apo-euphol) derivative possessing an eight carbons side-chain with an oxygenated ring system isolated from neem. Moreover, it is the first instance of the isolation of an 11-hydroxy triterpenoid from any of the various parts of neem.