Prontosan wound irrigation and gel: management of chronic wounds

Br J Nurs. 2006;15(22):1222, 1224-8. doi: 10.12968/bjon.2006.15.22.22559.


Chronic wounds present a challenge that is costly in terms of quality of life to the patient and in financial terms for the NHS. Several factors contribute to the development of a chronic wound, in particular the influence of bacteria as a biofilm within the wound environment. Irrigating a wound with normal saline has long been advocated as the most appropriate method of wound irrigation but biofilms are now known to be resistant to this method of cleansing. A small (10 patient) evaluation of the use of Prontosan in patients whose duration of chronic wounds exceeded 1 year has demonstrated that Prontosan wound irrigation and Prontosan gel are an appropriate alternative for cleaning, moistening and decontaminating encrusted, contaminated and chronic skin wounds, and can have a dramatic influence of the quality of life for such patients. This article discusses the cause of chronicity within a wound and discusses in depth three of the ten patients in the evaluation.

Publication types

  • Case Reports
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Administration, Cutaneous
  • Aged
  • Aged, 80 and over
  • Betaine / therapeutic use
  • Biguanides / therapeutic use*
  • Biofilms
  • Chronic Disease
  • Drug Combinations
  • Female
  • Gels
  • Humans
  • Infection Control / methods
  • Male
  • Quality of Life
  • Silver Compounds / therapeutic use
  • Skin Care / methods*
  • Skin Care / nursing
  • Surface-Active Agents / therapeutic use*
  • Therapeutic Irrigation / methods*
  • Therapeutic Irrigation / nursing
  • Treatment Outcome
  • Undecylenic Acids / therapeutic use
  • Wound Healing
  • Wound Infection / prevention & control*
  • Wound Infection / psychology


  • Biguanides
  • Drug Combinations
  • Gels
  • Silver Compounds
  • Surface-Active Agents
  • Undecylenic Acids
  • polihexanide
  • Betaine