Offering to share: how to put heads together in autism neuroimaging

J Autism Dev Disord. 2008 Jan;38(1):2-13. doi: 10.1007/s10803-006-0352-2. Epub 2007 Mar 9.


Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.

MeSH terms

  • Autistic Disorder / diagnosis*
  • Autistic Disorder / epidemiology
  • Brain / abnormalities*
  • Brain / diagnostic imaging*
  • Child
  • Cognition Disorders / diagnosis
  • Cognition Disorders / epidemiology
  • Cooperative Behavior*
  • Female
  • Humans
  • Interprofessional Relations
  • Magnetic Resonance Imaging
  • Male
  • Neuropsychological Tests
  • Phenotype
  • Positron-Emission Tomography
  • Social Perception