Antibiotic treatment of venereal disease and Reiter's syndrome in a Greenland population

Arthritis Rheum. 1992 Feb;35(2):190-4. doi: 10.1002/art.1780350210.


Objective: To assess the effects of antibiotic treatment of urethritis or cervicitis on the incidence of recurrences of articular symptoms in Reiter's syndrome patients.

Methods: Retrospective evaluation of the medical charts of 109 patients living in Greenland.

Results: Thirty-seven percent of the episodes of genitourinary tract inflammation that were not treated or were treated with penicillin were followed by arthritis, compared with 10% of those treated with tetracycline or erythromycin.

Conclusion: Antibiotics active against Chlamydia trachomatis reduced the risk of postvenereal arthritis in the population studied.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Arthritis / epidemiology
  • Arthritis / prevention & control*
  • Arthritis, Reactive / drug therapy*
  • Erythromycin / therapeutic use
  • Female
  • Greenland / ethnology
  • Humans
  • Incidence
  • Inuit
  • Male
  • Penicillins / therapeutic use*
  • Recurrence
  • Retrospective Studies
  • Sexually Transmitted Diseases / drug therapy*
  • Tetracycline / therapeutic use
  • Urethritis / drug therapy*
  • Uterine Cervicitis / drug therapy*


  • Penicillins
  • Erythromycin
  • Tetracycline