Abstract
MisL is a Salmonella enterica serotype Typhimurium fibronectin binding protein whose expression is induced during infection of mice. T-POP transposon mutagenesis identified marT as a positive regulatory element controlling expression of a misL::lacZYA transcriptional fusion. Gel shift analysis identified MarT as a transcriptional activator of the misL promoter.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Bacterial Proteins / genetics*
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Bacterial Proteins / metabolism*
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Gene Expression Regulation, Bacterial
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Lac Operon
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Membrane Transport Proteins / genetics*
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Membrane Transport Proteins / metabolism*
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Mutagenesis, Insertional
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Promoter Regions, Genetic / physiology
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Salmonella typhimurium / genetics*
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Salmonella typhimurium / metabolism*
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Trans-Activators / genetics
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Trans-Activators / metabolism*
Substances
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Bacterial Proteins
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Membrane Transport Proteins
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MisL protein, Salmonella enterica
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Trans-Activators