[Gynecomastia as a complication of hormonotherapy for prostate cancer: effect of prophylactic breast irradiation]

Harefuah. 2007 Feb;146(2):126-8, 164-5.
[Article in Hebrew]


Gynecomastia is a benign condition characterized by proliferation of mammary glandular tissue. Hormonotherapy with bicalutamide for prostate cancer is one of the causes of gynecomastia. The well known aim of treatment is to decrease psychological distress and to improve cosmetic appearance. Prophylactic breast irradiation may prevent the appearance of gynecomastia.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Androgen Antagonists / adverse effects*
  • Anilides / adverse effects*
  • Breast / radiation effects*
  • Gynecomastia / chemically induced*
  • Gynecomastia / prevention & control
  • Humans
  • Male
  • Nitriles / adverse effects*
  • Prostatic Neoplasms / drug therapy*
  • Tosyl Compounds / adverse effects*


  • Androgen Antagonists
  • Anilides
  • Nitriles
  • Tosyl Compounds
  • bicalutamide