Respiratory polygraphy with actigraphy in the diagnosis of sleep apnea-hypopnea syndrome

Chest. 2007 Mar;131(3):725-732. doi: 10.1378/chest.06-1604.


Objective: To determine the utility and reliability of a respiratory polygraphy (RP) device with actigraphy (Apnoescreen II; Erich Jaeger GMBH & CoKg; Wuerzburg, Germany) in the diagnosis of sleep apnea-hypopnea syndrome (SAHS).

Design: A prospective randomized study with blinded analysis.

Patients: Sixty-two patients with suspected SAHS.

Measurements: the following two RP studies were performed: one in the sleep laboratory (sleep laboratory RP [LRP]), simultaneously with polysomnography; and the other at home (home RP [HRP]). To study the interobserver reliability of RP, two manual analyses were carried out by two different researchers.

Results: In LRP, when the respiratory disturbance index was calculated using the total sleep time estimated by actigraphy (RDI) as a denominator, the sensitivity ranged between 94.6% and 100%, and the specificity between 88% and 96.7% for the different cutoff points of the apnea-hypopnea indexes studied. When the respiratory disturbance index was calculated according to the total recording time (RDITRT), the sensitivity was slightly lower (91.6 to 96.9%) and the specificity was similar (92 to 96.7%). In HRP, the sensitivity of the RDI ranged between 83.8% and 95.8%, and the specificity between 92% and 100%, whereas, when the RDITRT was used, the sensitivity was between 83.8% and 87.5%, and the specificity was between 94.7% and 100%. With regard to interobserver reliability, the intraclass correlation coefficient for the RDI of the two analyses of the RP was 0.99 for both LPR and HPR.

Conclusion: HPR is an effective and reliable technique for the diagnosis of SAHS, although it is less sensitive than LRP. Wrist actigraphy improves the results of HRP only slightly.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Equipment Design
  • Female
  • Humans
  • Male
  • Middle Aged
  • Monitoring, Ambulatory / instrumentation*
  • Observer Variation
  • Polysomnography / instrumentation*
  • Prospective Studies
  • Pulmonary Ventilation / physiology*
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation*
  • Sleep Apnea, Obstructive / diagnosis*
  • Sleep Apnea, Obstructive / physiopathology
  • Software
  • Statistics as Topic