Phototherapy and the brain-stem auditory evoked response in neonatal hyperbilirubinemia

J Pediatr. 1992 Feb;120(2 Pt 1):306-8. doi: 10.1016/s0022-3476(05)80450-0.


The latencies of peak V and interpeaks I-V and III-V in the brain-stem auditory evoked response of infants with hyperbilirubinemia before phototherapy were significantly greater than those in a control group of infants. These values of the brain stem auditory-evoked response improved significantly during phototherapy and correlated significantly with the declining bilirubin levels. Improvement continued after phototherapy, despite a rebound of serum bilirubin concentrations.

MeSH terms

  • Bilirubin / blood
  • Evoked Potentials, Auditory, Brain Stem*
  • Humans
  • Infant, Newborn
  • Jaundice, Neonatal / blood
  • Jaundice, Neonatal / physiopathology
  • Jaundice, Neonatal / therapy*
  • Phototherapy*
  • Reaction Time


  • Bilirubin