Combining classical HRV indices with wavelet entropy measures improves to performance in diagnosing congestive heart failure

Comput Biol Med. 2007 Oct;37(10):1502-10. doi: 10.1016/j.compbiomed.2007.01.012. Epub 2007 Mar 13.

Abstract

In this study, best combination of short-term heart rate variability (HRV) measures are sought for to distinguish 29 patients with congestive heart failure (CHF) from 54 healthy subjects in the control group. In the analysis performed, in addition to the standard HRV measures, wavelet entropy measures are also used. A genetic algorithm is used to select the best ones from among all possible combinations of these measures. A k-nearest neighbor classifier is used to evaluate the performance of the feature combinations in classifying these two groups. The results imply that two combinations of all HRV measures, both of which include wavelet entropy measures, have the highest discrimination power in terms of sensitivity and specificity values.

MeSH terms

  • Adult
  • Aged
  • Algorithms*
  • Analysis of Variance
  • Case-Control Studies
  • Databases, Factual
  • Electrocardiography / statistics & numerical data
  • Female
  • Heart Failure / diagnosis*
  • Heart Failure / physiopathology*
  • Heart Rate / physiology*
  • Humans
  • Male
  • Middle Aged
  • Sensitivity and Specificity
  • Software Design