The machines that divide and fuse mitochondria

Annu Rev Biochem. 2007;76:751-80. doi: 10.1146/annurev.biochem.76.071905.090048.

Abstract

Mitochondria are derived from eubacteria; however, in most eukaryotes, novel mechanisms for the propagation of this organelle and its genome have evolved. This review focuses on what is currently known about the novel molecular machines that divide and fuse mitochondria.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Apoptosis / physiology
  • Carrier Proteins / chemistry
  • Carrier Proteins / metabolism
  • Dynamin I / metabolism
  • GTP Phosphohydrolases / metabolism*
  • Intracellular Membranes / metabolism
  • Intracellular Membranes / ultrastructure
  • Mitochondria / metabolism*
  • Mitochondria / ultrastructure
  • Mitochondrial Proteins / chemistry
  • Mitochondrial Proteins / genetics
  • Mitochondrial Proteins / metabolism
  • Models, Molecular
  • Saccharomyces cerevisiae Proteins / chemistry
  • Saccharomyces cerevisiae Proteins / metabolism

Substances

  • Adaptor Proteins, Signal Transducing
  • Caf4 protein, S cerevisiae
  • Carrier Proteins
  • MDV1 protein, S cerevisiae
  • Mitochondrial Proteins
  • Saccharomyces cerevisiae Proteins
  • Dynamin I
  • GTP Phosphohydrolases