Carotid cavernous fistula in CNS choriocarcinoma

Pediatr Blood Cancer. 2008 Apr;50(4):893-5. doi: 10.1002/pbc.21178.


Carotid artery-cavernous sinus fistulas (CCFs) are infrequently reported in the pediatric population, and are rarely reported in conjunction with CNS neoplasms. The authors present a 7-year-old girl with CNS choriocarcinoma who acutely developed left eye proptosis and conjunctival injection. Computed tomography angiography revealed a CCF, which was endovascularly embolized with detachable coils. There may be a direct cause-and-effect relationship between choriocarcinoma and development of CCFs.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Brain Neoplasms / complications*
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / pathology
  • Carotid-Cavernous Sinus Fistula / etiology*
  • Carotid-Cavernous Sinus Fistula / pathology
  • Carotid-Cavernous Sinus Fistula / therapy
  • Cerebral Angiography
  • Child
  • Choriocarcinoma / complications*
  • Choriocarcinoma / drug therapy
  • Choriocarcinoma / pathology
  • Embolization, Therapeutic
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Pregnancy