The open lung concept of mechanical ventilation: the role of recruitment and stabilization

Crit Care Clin. 2007 Apr;23(2):241-50, ix-x. doi: 10.1016/j.ccc.2006.12.001.


This article describes the pathophysiologic basis and clinical role for lung recruitment maneuvers. It reviews the literature and presents the authors' clinical experience of over 15 years in the collaboration between Erasmus MC and the University of Rochester. The authors are hopeful that these lung-protective strategies are presented in a useful format that may be useful to the practicing intensivist, thus bringing laboratory and clinical research to bedside practice.

Publication types

  • Review

MeSH terms

  • Humans
  • Intensive Care Units*
  • Positive-Pressure Respiration / methods*
  • Positive-Pressure Respiration / statistics & numerical data
  • Pulmonary Alveoli / physiology*
  • Respiration, Artificial / adverse effects
  • Respiration, Artificial / statistics & numerical data*
  • Respiratory Distress Syndrome / etiology
  • Respiratory Distress Syndrome / prevention & control*