Human alveolar echinococcosis in Slovenia

Clin Microbiol Infect. 2007 May;13(5):544-6. doi: 10.1111/j.1469-0691.2007.01701.x. Epub 2007 Mar 19.


Between January 2001 and December 2005, 1263 patients suspected of having echinococcosis were screened serologically by indirect haemagglutination assay (IHA). IHA-positive patient sera were then retested by western blot for confirmation and differentiation between Echinococcus granulosus and Echinococcus multilocularis infection. Of 43 sera confirmed as Echinococcus-positive, nine appeared to be specific for alveolar echinococcosis (AE) caused by E. multilocularis. AE-positive serological results corresponded to the clinical and/or imaging findings concerning the patients' liver cysts. The detected incidence of AE was 0.45/10(5) inhabitants, which suggests that clinicians and health authorities in Slovenia should give greater attention to AE in the future.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Animals
  • Blotting, Western
  • Echinococcosis, Hepatic / diagnosis
  • Echinococcosis, Hepatic / epidemiology
  • Echinococcosis, Hepatic / immunology
  • Echinococcosis, Hepatic / parasitology*
  • Echinococcus multilocularis / immunology
  • Echinococcus multilocularis / pathogenicity*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunologic Tests / methods
  • Male
  • Middle Aged
  • Slovenia / epidemiology