What's wrong with drug screening today

Garry P Nolan

doi:10.1038/nchembio0407-187

What's wrong with drug screening today

Nat Chem Biol. 2007 Apr;3(4):187-91. doi: 10.1038/nchembio0407-187.

Author

Garry P Nolan¹

Affiliation

¹ Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305, USA. gnolan@stanford.edu

PMID: 17372598
DOI: 10.1038/nchembio0407-187

Abstract

Drug screening in the immediate term will be best accomplished by early use of primary cells in which the target of the screen is a network of proteins measured in populations of single cells.

MeSH terms

Animals
Drug Approval*
Drug Design*
Drug Evaluation, Preclinical* / methods
Drug Evaluation, Preclinical* / standards
Humans
Models, Theoretical*