Non-invasive management of impotence with transcutaneous nitroglycerin

Br J Urol. 1992 Jan;69(1):88-90. doi: 10.1111/j.1464-410x.1992.tb15466.x.


Nitroglycerin plasters were applied to the penis in 10 impotent men and the erectile effect assessed. During laboratory testing all patients achieved an erectile response. Self-administration of nitroglycerin patches restored potency in 4 patients and was preferred to papaverine auto-injection by 3. Headache was a common side effect during initial administration. An attempt to treat impotence with nitroglycerin plaster seems worthwhile before starting extensive investigations or invasive treatment.

MeSH terms

  • Administration, Cutaneous
  • Aged
  • Erectile Dysfunction / drug therapy*
  • Headache / chemically induced
  • Humans
  • Male
  • Middle Aged
  • Nitroglycerin / administration & dosage*
  • Nitroglycerin / adverse effects
  • Nitroglycerin / therapeutic use
  • Penile Erection / drug effects


  • Nitroglycerin