Out of Africa: what can we learn from HIV-2 about protective immunity to HIV-1?

Nat Immunol. 2007 Apr;8(4):329-31. doi: 10.1038/ni0407-329.


Most people infected with human immunodeficiency virus 2 (HIV-2) do not progress to disease, even though the minority who do cannot be distinguished clinically from HIV-1-infected patients. Here we review what is known about the basis of viral control in HIV-2 infection.

Publication types

  • Review

MeSH terms

  • Animals
  • Cercocebus atys
  • Disease Progression
  • Guinea-Bissau
  • HIV Infections / immunology*
  • HIV Infections / virology
  • HIV-1 / immunology*
  • HIV-2 / immunology*
  • Humans
  • Simian Acquired Immunodeficiency Syndrome / immunology
  • Simian Acquired Immunodeficiency Syndrome / virology
  • Simian Immunodeficiency Virus / immunology