Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998

Dev Med Child Neurol. 2007 Apr;49(4):246-51. doi: 10.1111/j.1469-8749.2007.00246.x.


The aim of this study was to describe the epidemiology, aetiology, and clinical findings in dyskinetic cerebral palsy (CP)in a population-based follow-up study of children born between 1991 and 1998. Age range at ascertainment was 4 to 8 years and prevalence was 0.27 per 1000 live-births. Forty-eight children were examined (27 males, 21 females; mean age 9y, range 5-13y). Thirty-nine had dystonic CP and nine a choreo-athetotic subtype. Primitive reflexes were present in 43 children and spasticity in 33. Gross Motor Function Classification System levels were: Level IV, n= 10 and Level V, n= 28. The rate of learning disability (n= 35) and epilepsy (n= 30) increased with the severity of the motor disability. Thirty-eight children had anarthria. Peri- or neonatal adverse events had been present in 34 of 42 children born at >or=34 weeks' gestation. Motor impairment was most severe in this group. Placental abruption or uterine rupture had occurred in 8 participants and 19 of the 42 near-term/term children required assisted ventilation, compared with 1% and 12% respectively in other CP types. Neuroimaging in 39 children born at >or=34 weeks revealed isolated, late third trimester lesions in 24 and a combination of early and late third trimester lesions in seven. Dyskinetic CP is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abruptio Placentae / diagnosis
  • Abruptio Placentae / epidemiology
  • Adolescent
  • Asphyxia Neonatorum / diagnosis
  • Asphyxia Neonatorum / epidemiology
  • Brain / pathology
  • Cerebral Palsy / diagnosis
  • Cerebral Palsy / epidemiology*
  • Cerebral Palsy / etiology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Hypoxia-Ischemia, Brain / diagnosis
  • Hypoxia-Ischemia, Brain / epidemiology
  • Infant
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Neurologic Examination
  • Population Surveillance
  • Pregnancy
  • Risk Factors
  • Sweden
  • Tomography, X-Ray Computed
  • Uterine Rupture / diagnosis
  • Uterine Rupture / epidemiology