Lipid rafts and membrane traffic

FEBS Lett. 2007 May 22;581(11):2098-104. doi: 10.1016/j.febslet.2007.03.019. Epub 2007 Mar 15.


Membrane rafts are regions of increased lipid acyl chain order that differ in their lipid and protein composition from the surrounding membrane. By providing an additional level of compartmentalization they have been proposed to serve many functions in cellular signal transduction and trafficking. We will review their potential involvement in different forms of membrane traffic, explicitly excluding signalling, and discuss select aspects of the raft hypothesis in its current form.

Publication types

  • Review

MeSH terms

  • Cell Membrane* / chemistry
  • Cell Membrane* / metabolism
  • Cell Membrane* / ultrastructure
  • Cell Movement / physiology
  • Endocytosis / physiology
  • Exocytosis / physiology
  • Membrane Microdomains / chemistry
  • Membrane Microdomains / metabolism*
  • Protein Transport / physiology*