Soft tissue elastometer

Med Eng Phys. 2008 Mar;30(2):206-12. doi: 10.1016/j.medengphy.2007.02.007. Epub 2007 Mar 23.


We have developed a device entitled the 'Tissue Elastometer' (TE) for evaluating the Young's modulus of soft tissues. Soft tissue specimens are compressed between the object plate of an electronic balance and a linearly actuated indenter with a small rounded tip. The hardware of the device was designed such that a deformation model for semi-infinite media is applicable for calculating the Young's modulus of test specimens from their collected force-displacement data. Force-elongation measurements were performed on long strips of cured silicone mixtures to produce calibrated, tissue-mimicking test samples for the TE in a Young's modulus range of 10-400 kPa. When tested with the TE, the Young's moduli of the silicone samples demonstrated accuracy to within 1-10% of their calibrated values. Testing on excised tissue samples (fresh store-bought poultry breast; bovine liver, kidneys, hind shanks; porcine) was also performed, and a repeatability of elasticity measurements was demonstrated in the range of 8-14%. Results indicate that the TE can be effectively used in laboratory and clinical environments to evaluate the elasticity modulus of tissues.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Biomedical Engineering
  • Cattle
  • Connective Tissue / physiology*
  • Elasticity Imaging Techniques / instrumentation*
  • Elasticity Imaging Techniques / methods
  • Elasticity*
  • Kidney / physiology
  • Liver / physiology
  • Muscles / physiology
  • Poultry
  • Silicone Elastomers
  • Sus scrofa


  • Silicone Elastomers