Effects of a home-based intervention program on anxiety and depression 6 months after coronary artery bypass grafting: a randomized controlled trial

J Psychosom Res. 2007 Apr;62(4):411-8. doi: 10.1016/j.jpsychores.2006.11.010.


Objective: The objective of this study was to evaluate the effects of a home-based intervention program (HBIP) on anxiety and depression 6 months after coronary artery bypass grafting (CABG).

Methods: In a prospective randomized controlled trial, 203 elective CABG patients were included. An HBIP structured for respondents in the intervention group was performed 2 and 4 weeks after surgery. Anxiety and depression symptoms were measured by the Hospital Anxiety and Depression Scale (HADS) in both patient groups before surgery, 6 weeks after surgery, and 6 months after surgery.

Results: A total of 185 patients completed the study: 93 patients in the intervention group and 92 patients in the control group. On 6-week and 6-month follow-ups, significant improvements in anxiety and depression symptoms were found in both groups. These improvements did not differ significantly between the groups. However, in a predefined subgroup of patients with anxiety and/or depression symptoms at baseline (n=65), improvement was significantly larger in the intervention group (n=29) than in the control group (n=36) after 6 months (P<.05).

Conclusions: Patients experiencing high levels of psychological distress before CABG surgery benefited from a structured informational and psychological HBIP. Implementation of psychological screens of patients scheduled for CABG might serve to identify patients experiencing anxiety and/or depression. These patients could then be targeted to receive individualized HBIP.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Anxiety / diagnosis
  • Anxiety / nursing*
  • Anxiety / psychology
  • Community Health Nursing*
  • Coronary Artery Bypass / nursing*
  • Coronary Artery Bypass / psychology
  • Depression / diagnosis
  • Depression / nursing*
  • Depression / psychology
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Mass Screening / nursing
  • Middle Aged
  • Patient Education as Topic*
  • Personality Inventory
  • Prospective Studies
  • Social Support*