Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 14 (4), 347-8

Mouse Piwi-interacting RNAs Are 2'-O-methylated at Their 3' Termini

Affiliations

Mouse Piwi-interacting RNAs Are 2'-O-methylated at Their 3' Termini

Yohei Kirino et al. Nat Struct Mol Biol.

Abstract

Piwi-interacting RNAs (piRNAs) are a novel class of small RNAs that are expressed specifically and abundantly in male germ cells. Here we report that the 3' termini of piRNAs are 2'-O-methylated; this modification may have important implications for the biogenesis and function of piRNAs.

Comment in

  • A Marked End
    X Chen. Nat Struct Mol Biol 14 (4), 259-60. PMID 17410089.
    microRNAs (miRNAs) and small interfering RNAs from plants are 2′-O-methylated at their 3′ termini. Although miRNAs from animals are not methylated, two studies sho …

Similar articles

See all similar articles

Cited by 118 PubMed Central articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback