The Effect of Cinnamon on A1C Among Adolescents With Type 1 Diabetes

Diabetes Care. 2007 Apr;30(4):813-6. doi: 10.2337/dc06-1871.

Abstract

Objective: The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type 1 diabetes.

Research design and methods: Using a prospective, double-blind, placebo-controlled design, 72 adolescent type 1 diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. A1C, total daily insulin intake, and adverse events were recorded and compared between groups.

Results: There were no significant differences in final A1C (8.8 vs. 8.7, P = 0.88), change in A1C (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms.

Conclusions: Cinnamon is not effective for improving glycemic control in adolescents with type 1 diabetes.

Trial registration: ClinicalTrials.gov NCT00365170.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cinnamomum zeylanicum*
  • Diabetes Mellitus, Type 1 / blood*
  • Diabetes Mellitus, Type 1 / drug therapy
  • Double-Blind Method
  • Female
  • Glycated Hemoglobin A / metabolism*
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Male
  • Phytotherapy*
  • Prospective Studies

Substances

  • Glycated Hemoglobin A
  • Hypoglycemic Agents
  • Insulin

Associated data

  • ClinicalTrials.gov/NCT00365170