Wound therapy with autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers affecting the lower limbs

Int J Clin Pract. 2007 Apr;61(4):690-2. doi: 10.1111/j.1742-1241.2007.01303.x.


Previous studies suggest that autologous transplantation of bone marrow mononuclear cells is safe and effective in inducing therapeutic angiogenesis in patients with peripheral arterial occlusive disease (PAOD). Here we discuss a multidisciplinary approach to treating PAOD with a focus on the use of angiological diagnostic tools. We conclude that our autologous stem cell therapy is working in this patient and it is a potential new therapeutic option for diabetic patients with chronic foot ulcers induced by critical limb ischaemia.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Diabetes Mellitus, Type 2 / complications
  • Diabetic Foot / therapy*
  • Humans
  • Ischemia / complications*
  • Leg / blood supply*
  • Male
  • Middle Aged
  • Stem Cell Transplantation / methods*
  • Treatment Outcome