Double stenting of oesophagus and airways in palliative treatment of patients with oesophageal cancer is efficient but associated with a high morbidity

Aliment Pharmacol Ther. 2007 Apr 15;25(8):955-63. doi: 10.1111/j.1365-2036.2007.03280.x.

Abstract

Background: Double stenting of oesophagus and airways may be required in palliative treatment of patients with locally advanced oesophageal cancer.

Aim: To assess feasibility, efficacy and complications occurring in patients with locally advanced oesophageal cancer receiving both oesophagus and airways stenting.

Methods: In one single centre between 1997 and 2005, among 180 patients with locally advanced oesophageal cancer treated by the palliative placement of a self-expanding metal stent, patients requiring double stenting of oesophagus and airways were identified. Clinical efficacy, complications and survival were retrospectively collected.

Results: Fifteen patients (8.3% of 180) required a double stenting at follow-up. Symptomatic efficacy of oesophagus and airways stenting was 86.7% for dysphagia and 100% for dyspnoea. Median survival after the second stent insertion was 99 days. Life-threatening early complications occurred in three patients after double stenting (20%), including two deaths following oesophageal perforation and massive haemoptysis, respectively. Procedure-related mortality was 13.3%.

Conclusions: Double stenting of oesophagus and airways is feasible in patients with locally advanced oesophageal cancer, with a relevant clinical efficacy. However, early major complications including procedure-related death may occur in as many as 20% of patients. This treatment should be reserved to very selected patients with severe symptoms and end-stage disease.

MeSH terms

  • Adult
  • Aged
  • Deglutition Disorders / drug therapy*
  • Deglutition Disorders / prevention & control
  • Esophageal Neoplasms / complications
  • Esophageal Neoplasms / mortality
  • Esophageal Neoplasms / surgery*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Palliative Care / methods*
  • Palliative Care / standards
  • Stents / adverse effects*
  • Stents / standards
  • Survival Rate
  • Treatment Outcome