Superior vena cava syndrome with central venous catheter for chemotherapy treated successfully with fibrinolysis

Clin Transl Oncol. 2007 Mar;9(3):198-200. doi: 10.1007/s12094-007-0036-1.

Abstract

Recently, there has been an increase in the number of cases of superior vena cava (SVC) syndrome associated with chronic indwelling central venous catheters. Fibrinolytic therapy and endovascular treatment are currently achieving good results. We present a case history of a patient with SVC with a catheter used for chemotherapy, which was successfully treated with catheter-directed (intraclot) infusion thrombolytic therapy with urokinase.

Publication types

  • Case Reports

MeSH terms

  • Anticoagulants / administration & dosage
  • Anticoagulants / therapeutic use
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / therapeutic use
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / radiotherapy
  • Breast Neoplasms / surgery
  • Catheterization, Central Venous / adverse effects*
  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Coumarins / administration & dosage
  • Coumarins / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Fibrinolytic Agents / administration & dosage
  • Fibrinolytic Agents / therapeutic use*
  • Humans
  • Infusions, Intravenous
  • Mastectomy, Segmental
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Radiotherapy, Adjuvant
  • Subclavian Vein
  • Superior Vena Cava Syndrome / diagnosis
  • Superior Vena Cava Syndrome / drug therapy*
  • Superior Vena Cava Syndrome / etiology
  • Thrombolytic Therapy / methods*
  • Urokinase-Type Plasminogen Activator / administration & dosage
  • Urokinase-Type Plasminogen Activator / therapeutic use*

Substances

  • Anticoagulants
  • Antineoplastic Agents
  • Coumarins
  • Fibrinolytic Agents
  • dicumarin
  • Urokinase-Type Plasminogen Activator
  • Methylprednisolone