Orbital embryonal rhabdomyosarcoma in association with neurofibromatosis type 1

Ophthalmic Plast Reconstr Surg. Mar-Apr 2007;23(2):147-8. doi: 10.1097/IOP.0b013e318032af94.

Abstract

A 20-month-old child with systemic features of neurofibromatosis type 1 presented with sudden-onset proptosis. Biopsy and histopathology confirmed the diagnosis of an embryonal rhabdomyosarcoma. The tumor regressed completely with chemotherapy and external beam radiotherapy. This case highlights the association of rhabdomyosarcoma with neurofibromatosis type 1.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Dose Fractionation, Radiation
  • Exophthalmos / diagnosis
  • Female
  • Humans
  • Infant
  • Neoplasms, Second Primary / diagnostic imaging
  • Neoplasms, Second Primary / pathology*
  • Neoplasms, Second Primary / therapy
  • Neurofibromatosis 1 / diagnostic imaging
  • Neurofibromatosis 1 / pathology*
  • Neurofibromatosis 1 / therapy
  • Orbital Neoplasms / diagnostic imaging
  • Orbital Neoplasms / pathology*
  • Orbital Neoplasms / therapy
  • Rhabdomyosarcoma, Embryonal / diagnostic imaging
  • Rhabdomyosarcoma, Embryonal / pathology*
  • Rhabdomyosarcoma, Embryonal / therapy
  • Tomography, X-Ray Computed