Abstract
Tibial hemimelia with ectrodactyly is reported for the first time in monozygotic female twins with a positive family history for limb anomalies. This very rare autosomal dominant condition is known to be associated with a highly variable phenotype, as illustrated by the distinct clinical presentations, despite identical genotype.
MeSH terms
-
Abnormalities, Multiple / diagnostic imaging
-
Amputation, Surgical
-
Diseases in Twins / genetics*
-
Diseases in Twins / surgery
-
Female
-
Foot Deformities, Congenital / diagnostic imaging
-
Foot Deformities, Congenital / genetics*
-
Foot Deformities, Congenital / surgery
-
Hand Deformities, Congenital / genetics*
-
Humans
-
Infant
-
Pedigree
-
Phenotype
-
Radiography
-
Tibia / abnormalities*
-
Tibia / diagnostic imaging
-
Twins, Monozygotic