An efficient program for computing conditional maximum likelihood estimates and exact confidence limits for a common odds ratio

Epidemiology. 1991 Sep;2(5):359-62. doi: 10.1097/00001648-199109000-00008.


This paper describes a method and associated computer program for calculating exact confidence limits and P values, along with the conditional maximum likelihood estimate of the common odds ratio for a series of 2 x 2 tables. The program can be used to calculate exact estimates for matched data and is considerably faster than others currently available.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms
  • Case-Control Studies
  • Confidence Intervals*
  • Likelihood Functions*
  • Mathematics
  • Odds Ratio*
  • Software*