Acute dystonia induced by sulpiride

Clin Neuropharmacol. 1991 Oct;14(5):463-4. doi: 10.1097/00002826-199110000-00012.


We report a 15-year-old boy who, after the administration of 100 mg i.v. of sulpiride, presented an acute dystonic reaction consisting of oculogyric crises, retrocollis, opysthotonus, and dystonic postures in the left arm and hand. The symptoms were reversed after the injection of biperiden. This side effect has not been described previously. Sulpiride can induce the same extrapyramidal adverse reactions as the classical neuroleptic drugs.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Dystonia / chemically induced*
  • Humans
  • Male
  • Sulpiride / adverse effects*


  • Sulpiride