Performance of a rapid assay (Binax NOW) for detection of respiratory syncytial virus at a children's hospital over a 3-year period

J Clin Microbiol. 2007 Jun;45(6):1993-5. doi: 10.1128/JCM.00279-07. Epub 2007 Apr 11.

Abstract

A rapid assay, Binax NOW RSV, was compared to viral culture for 14,756 pediatric respiratory specimens obtained from 2003 to 2006. There were 794 viral culture-confirmed respiratory syncytial virus infections. Sensitivity was 81%, and specificity was 93.2%. Sensitivity was greatest for neonates (91.1% versus 80.7% [P < 0.01]).

Publication types

  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Antigens, Viral / analysis*
  • Cell Line
  • Child
  • Child, Preschool
  • Chromatography / methods
  • Hospitals, Pediatric*
  • Humans
  • Immunologic Tests / methods
  • Infant
  • Infant, Newborn
  • Reagent Kits, Diagnostic*
  • Respiratory Syncytial Virus Infections / diagnosis*
  • Respiratory Syncytial Virus Infections / virology
  • Respiratory Syncytial Virus, Human / immunology
  • Respiratory Syncytial Virus, Human / isolation & purification*
  • Respiratory System / virology
  • Sensitivity and Specificity
  • Time Factors
  • Virus Cultivation

Substances

  • Antigens, Viral
  • Reagent Kits, Diagnostic