Prognostic factors for complications following pulmonary resection: pre-albumin analysis, time on mechanical ventilation, and other factors

J Bras Pneumol. 2006 Nov-Dec;32(6):489-94. doi: 10.1590/s1806-37132006000600004.
[Article in English, Portuguese]

Abstract

Objective: To determine whether pre-operative nutritional status and post-operative time on mechanical ventilation, as well as others factors, are correlated with post-operative complications (general or pulmonary) in patients undergoing elective thoracic surgery.

Methods: A prospective study was conducted, involving 71 patients undergoing elective pulmonary resection. The data collected pre-operatively included gender, age, smoking status, pre-albumin level, lymphocyte count, and body mass index. The peri-operative data included type of surgery and surgical time, as well as post-operative time on mechanical ventilation.

Results: Post-operative complications were found to correlate with low pre-albumin concentration, type of resection, surgical time, and post-operative time on mechanical ventilation. Surgical time and post-operative time on mechanical ventilation were also implicated in the post-operative pulmonary complications observed in 22 (30.99%) of the patients studied.

Conclusion: Our results suggest that pre-albumin concentration, type of surgery and surgical time, as well as post-operative time on mechanical ventilation, serve as predictive indices of post-operative complications in patients undergoing elective pulmonary resection. In the analysis of the post-operative pulmonary complications, statistically significant correlations were found between such complications and increases in surgical time or post-operative time on mechanical ventilation.

MeSH terms

  • Adult
  • Aged
  • Albumins / analysis
  • Body Mass Index
  • Cohort Studies
  • Elective Surgical Procedures / adverse effects*
  • Female
  • Humans
  • Lung Diseases, Fungal / surgery*
  • Lung Neoplasms / surgery*
  • Male
  • Middle Aged
  • Nutritional Status
  • Pneumonectomy / adverse effects*
  • Predictive Value of Tests
  • Prognosis
  • Prospective Studies
  • Respiration, Artificial / adverse effects
  • Risk Factors
  • Time Factors

Substances

  • Albumins