Organization of the mitochondrial genome in the dinoflagellate Amphidinium carterae

Mol Biol Evol. 2007 Jul;24(7):1528-36. doi: 10.1093/molbev/msm074. Epub 2007 Apr 17.

Abstract

We have characterized the mitochondrial genome of the dinoflagellate Amphidinium carterae. It contains just 3 identifiable protein-coding genes: cox1, cox3, and cob. No evidence for rRNA or tRNA genes was found. Expressed sequence tags (EST) sequences for the 3 genes suggest that RNA editing occurs in 2 cases removing an in-frame stop codon. Two of the transcripts (cob and cox1) lack a stop codon at the end of the gene. The genome contains a large amount of noncoding DNA including many fragmented copies of all the 3 genes and large numbers of inverted repeats. The genome, which contains about 70% AT, has undergone extensive recombination, possibly due to the inverted repeats. The highly reduced mitochondrial gene content supports the relationship of the dinoflagellates and apicomplexa as sister groups.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Dinoflagellida / genetics*
  • Evolution, Molecular
  • Genes, Mitochondrial*
  • Genomics
  • Molecular Sequence Data
  • RNA Editing
  • Sequence Analysis, DNA

Associated data

  • GENBANK/EF514766
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  • GENBANK/EF514796