Biopsy techniques and yields in diagnosing primary intraocular lymphoma

Int Ophthalmol. 2007 Aug;27(4):241-50. doi: 10.1007/s10792-007-9065-6. Epub 2007 Apr 18.


A review of current biopsy techniques that are used in obtaining specimens from which to make a diagnosis of primary intraocular lymphoma (PIOL) is presented. Methods for obtaining and subsequently testing vitrectomy specimens are discussed. In addition, the yields of external and internal approaches for obtaining chorioretinal tissue, and diagnostic vitrectomies, are reviewed.

Publication types

  • Research Support, N.I.H., Intramural
  • Review

MeSH terms

  • Biopsy / methods
  • Choroid / pathology
  • Eye Neoplasms / pathology*
  • Eye Neoplasms / surgery
  • Humans
  • Lymphoma / pathology*
  • Lymphoma / surgery
  • Reproducibility of Results
  • Retina / pathology