Interoceptive basis to craving

Neuron. 2007 Apr 19;54(2):183-6. doi: 10.1016/j.neuron.2007.03.024.


Awareness of one's physiology is an important component of emotion. How might these processes be related to addiction? In a recent issue of Science, Naqvi et al. demonstrated that smoking addiction is disrupted by damage to the insula cortex. This suggests that brain circuits mediating interoception also contribute to craving states.

MeSH terms

  • Brain / physiopathology*
  • Cerebral Cortex / physiopathology
  • Humans
  • Motivation
  • Neural Pathways
  • Smoking / physiopathology
  • Smoking Cessation
  • Substance-Related Disorders / physiopathology*
  • Substance-Related Disorders / psychology*