[Carnosine and diseases of central nervous system]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007 Mar;36(2):199-203.
[Article in Chinese]

Abstract

The naturally-occurring dipeptide carnosine (beta-alanyl-L-histidine) is found exclusively in animal tissues, such as brain and skeletal muscle tissues. Carnosine is a potent hydrophilic antioxidant, antiglycating agent, reactive oxygen species scavenger and pH-buffer. Recent reports suggest that carnosine has potential therapeutic applications in many diseases of central nervous system, such as Alzheimer's disease, Parkinson's disease and cerebral ischemic diseases. To investigate the relationship between carnosine and diseases of central nervous system, and to research and develop carnosine drugs will shed light on a new way for treatment of diseases of central nervous system.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Alzheimer Disease / drug therapy
  • Brain Diseases / drug therapy
  • Brain Ischemia / drug therapy
  • Carnosine / therapeutic use*
  • Central Nervous System Diseases / drug therapy*
  • Humans
  • Parkinson Disease / drug therapy

Substances

  • Carnosine