The Uppsala studies on developmental origins of health and disease

J Intern Med. 2007 May;261(5):426-36. doi: 10.1111/j.1365-2796.2007.01799.x.


Large-scale epidemiological studies on developmental origins of health running in Uppsala benefit from the accessibility of well-archived and high quality Swedish records, high participation rates in the surveys, and a long tradition of interdisciplinary research and international collaboration. The UBCoS Multigen study is unique in being able to study intergenerational determinants of health and health inequalities as 'forward in time' processes, starting at the beginning of the last century, whilst the Uppsala Family and ULSAM studies contribute evidence on gene-environment interactions and specific mechanisms of developmental origins of circulatory diseases.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Aged
  • Birth Weight
  • Blood Pressure / physiology
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology*
  • Cardiovascular Diseases / physiopathology
  • Cohort Studies
  • Databases, Factual
  • Family Health
  • Female
  • Fetal Growth Retardation / physiopathology
  • Humans
  • Male
  • Middle Aged
  • Pregnancy
  • Prenatal Exposure Delayed Effects* / physiopathology
  • Socioeconomic Factors
  • Sweden / epidemiology