Stem cell therapy-present status

Transplant Proc. 2007 Apr;39(3):694-9. doi: 10.1016/j.transproceed.2007.01.069.

Abstract

Stem cell research is a new field that is advancing at an incredible pace with new discoveries being reported from all over the world. Scientists have for years looked for ways to use stem cells to replace cells and tissues that are damaged or diseased. Stem cells are the foundation cells for every organ, tissue, and cell in the body. Stem cells are undifferentiated, "blank" cells that do not yet have a specific function. Under proper conditions, stem cells begin to develop into specialized tissues and organs. They are self-sustaining and can replicate themselves for long periods of time. Embryonic stem cells are pluripotent cells, isolated from the inner cell mass of the blastocyst-stage mammalian embryo. They have the ability to differentiate into several somatic or somatic-like functional cells such as neurons, hepatocytes, cardiomyocytes, and others. Adult stem cells are specialized cells found within many tissues of the body where they function in tissue homeostasis and repair. They are precursor cells capable of differentiation into several different cells. The knowledge of stem cells from various sources offered a new hope for the treatment of various diseases.

Publication types

  • Review

MeSH terms

  • Adult
  • Animals
  • Diabetes Mellitus / therapy
  • Embryonic Stem Cells / cytology
  • Heart Diseases / therapy
  • Humans
  • Liver / cytology
  • Mesoderm / cytology
  • Models, Animal
  • Models, Biological
  • Nervous System Diseases / therapy
  • Stem Cell Transplantation / ethnology
  • Stem Cell Transplantation / trends*