The German Physician Wilhelm Schüssler (1821-1898) developed a healing system called "Biochemie". Basically it had merely the character of a substitution therapy with mineral compounds and was based on physiological considerations by Jakob Moleschott (1822-1893) and Justus von Liebig (1803-1873) which were fundamental for the development of the scientific discipline of biochemistry as well. Schüssler himself, however, who had been educated in homoeopathy, introduced more and more immaterial or "biodynamic" explanations for the therapeutic effect of the mineral salt preparations. This attempt was continued by his successors, namely by Dietrich (called Dieter) Schöpwinkel (1876-1946) who enriched the system with new preparations as well as several theoretical aspects strongly related to the dynamic approach.