Nonoutbreak surveillance of group A streptococci causing invasive disease in Portugal identified internationally disseminated clones among members of a genetically heterogeneous population

J Clin Microbiol. 2007 Jun;45(6):2044-7. doi: 10.1128/JCM.00496-07. Epub 2007 Apr 25.


The typing of 160 invasive Streptococcus pyogenes isolates confirmed the importance of pulsed-field gel electrophoresis and multilocus sequence typing for defining clones. The results identified an extremely diverse population and highlighted the importance of both internationally disseminated and local clones not previously associated with invasive disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Bacterial Typing Techniques
  • Electrophoresis, Gel, Pulsed-Field
  • Genetic Variation*
  • Global Health
  • Humans
  • Middle Aged
  • Population Surveillance*
  • Portugal / epidemiology
  • Sequence Analysis, DNA
  • Serotyping
  • Streptococcal Infections / epidemiology*
  • Streptococcal Infections / microbiology
  • Streptococcus pyogenes / classification*
  • Streptococcus pyogenes / genetics
  • Streptococcus pyogenes / isolation & purification