Primary malignant lymphoma of the cranial vault

Acta Neurochir (Wien). 2007 Jun;149(6):601-4. doi: 10.1007/s00701-007-1156-7. Epub 2007 Apr 26.

Abstract

A 60-year-old woman presented with a subcutaneous mass on her scalp. Computed tomography (CT) showed a homogeneously enhanced mass of the parietal bone with both intra- and extra-calvarial extension and having destroyed the right parietal bone. The mass was hypointense on the T1-weighted magnetic resonance image, slightly hyperintense on the T2-weighted image and homogenously enhanced with Gd-DTPA. Bone scintigraphy showed prominent accumulation of radioisotopes in the scalp lesion. The tumour was removed, including the involved bone and dura mater. Histologic diagnosis was non-Hodgkin's B-cell lymphoma, and tumour cells had infiltrated into the dura mater. The patient was treated with radiotherapy and chemotherapy. She returned to ordinary daily life and has been well without recurrence for 3 years. Although primary malignant lymphoma of the cranial vault is rare, it should be considered in the differential diagnosis when a mass is encountered in the cranial vault. We have found only fourteen such cases in the literature, and we review these cases.

Publication types

  • Case Reports

MeSH terms

  • Chemotherapy, Adjuvant
  • Combined Modality Therapy
  • Contrast Media / administration & dosage
  • Female
  • Follow-Up Studies
  • Gadolinium DTPA
  • Humans
  • Lymphoma, Large B-Cell, Diffuse / diagnosis*
  • Lymphoma, Large B-Cell, Diffuse / pathology
  • Lymphoma, Large B-Cell, Diffuse / surgery
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Parietal Bone* / pathology
  • Radionuclide Imaging
  • Radiotherapy, Adjuvant
  • Skull Neoplasms / diagnosis*
  • Skull Neoplasms / pathology
  • Skull Neoplasms / surgery
  • Tomography, X-Ray Computed*

Substances

  • Contrast Media
  • Gadolinium DTPA