Runaway implantable defibrillator--a rare complication of radiation therapy

Pacing Clin Electrophysiol. 2007 May;30(5):716-8. doi: 10.1111/j.1540-8159.2007.00735.x.

Abstract

A case of a patient with runaway implantable cardioverter defibrillator (ICD) due to radiation therapy of a lung cancer is reported. This manifested as poorly tolerated wide complex tachycardia due to inappropriate rapid ventricular pacing, The event terminated with polymorphic VT, which inhibited pacing and ceased spontaneously before ICD discharge. The likely cause was corruption of device random access memory by ionizing radiation.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / radiotherapy*
  • Combined Modality Therapy
  • Death, Sudden, Cardiac / prevention & control
  • Defibrillators, Implantable*
  • Electrocardiography
  • Equipment Failure Analysis
  • Humans
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / radiotherapy*
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Radiotherapy / adverse effects*
  • Radiotherapy Dosage
  • Tachycardia, Ventricular / etiology*
  • Tachycardia, Ventricular / prevention & control