Superficial chemical peeling with salicylic Acid in facial dermatoses

J Coll Physicians Surg Pak. 2007 Apr;17(4):187-90.


Objective: To determine the effectiveness of salicylic acid chemical peeling in common dermatological conditions affecting face in people with predominant Fitzpatrick skin type IV and V.

Design: An interventional, quasi-experimental study.

Place and duration of study: Military Hospital, Rawalpindi and PAF Hospital, Sargodha, from July 2002 to June 2003.

Patients and methods: A total of 167 patients of either gender, aged between 13 to 60 years, having some facial dermatoses (melasma, acne vulgaris, postinflammatory hyperpigmentations, freckles, fine lines and wrinkles, post-inflammatory scars, actinic keratoses, and plane facial warts) were included. A series of eight weekly hospital based peeling sessions was conducted in all patients under standardized conditions with 30% salicylic acid. Clinical improvement in different disorders was evaluated by change in MASI score, decrease in the size of affected area and % reduction in lesions count. McNemar test was applied for data analysis.

Results: Majority of the patients showed moderate to excellent response. There was 35% to 63% improvement (p<0.05) in all dermatoses. Significant side effects, as feared in Asian skins were not observed.

Conclusion: Chemical peeling with salicylic acid is an effective and safe treatment modality in many superficial facial dermatoses.