Long-term follow up of infants with congenital diaphragmatic hernia

Semin Pediatr Surg. 2007 May;16(2):134-44. doi: 10.1053/j.sempedsurg.2007.01.009.


With improving treatment strategies for congenital diaphragmatic hernia (CDH) infants, an increase in survival of more severely affected patients can be expected. Consequently, more attention is now focused on long-term follow up of these patients. Many reports have emphasized associated morbidity, including pulmonary sequelae, neurodevelopmental deficits, gastrointestinal disorders, and other abnormalities. Therefore, survivors of CDH remain a complex patient population to care for throughout infancy and childhood, thus requiring long-term follow up. Much information has been provided from many centers regarding individual institutional improvements in overall survival. Few of these, however, have reported long-term follow up. The aim of this review is to describe the long-term outcome of survivors with CDH and to suggest a possible follow-up protocol for these patients.

Publication types

  • Review

MeSH terms

  • Central Nervous System Diseases / etiology
  • Follow-Up Studies
  • Gastrointestinal Diseases / etiology
  • Hernia, Diaphragmatic / therapy
  • Hernias, Diaphragmatic, Congenital*
  • Humans
  • Longitudinal Studies
  • Lung Diseases / etiology
  • Quality of Life
  • Survivors*
  • Treatment Outcome